BRAINIACS

Figure 1: Methodological approach of the BRAINIACS project: closely linking experiments, modeling, and simulation.

Brain tissue is not only one of the most important but also the most complex and compliant tissue in the human body. While long underestimated, increasing evidence confirms that mechanics plays a critical role in modulating brain function and dysfunction. The Emmy-Noether research group BRAINIACS – BRAIn mechaNIcs ACross Scales – aims to establish novel computational tools based on nonlinear continuum mechanics that can facilitate early diagnostics of neurological diseases and advance modern treatment strategies. We bridge the scales from known biological processes on the cellular scale to macroscopic pathologies apparent through modern imaging techniques.
To achieve this goal, our group combines experimental and microstructural analyses with continuum scale modeling and simulation. Performing experiments hand in hand with modeling and simulation allows us to continually optimize both experimental and numerical procedures. Through the simultaneous investigation of mechanics and microstructure, we aim to not only understand the regional variations in brain structure and function, but also to quantify the adaptation of cells to changes in their mechanical environment.
Solved within a finite element framework, those models will help us to foresee the behavior of brain tissue under physiological and pathological conditions, and to simulate progression of disease or mechanically-induced loss of brain function.

BRAINIACS lab video

Within the series '2 Minuten Wisssen' organized by the Technical Faculty of FAU, we got the chance to shoot a short movie about the exciting research topics students can work on when they study 'Mechanical Engineering' or a related course of study at FAU. Check out the short 2-minute video and lea...

In autumn 2021, FAU has started the new event series #WISSENWOLLEN, where scientists present their current projects and research results in a generally understandable way and respond to questions from the audience. On December 22, just before Christmas, PI Silvia Budday had the pleasure to talk ab...

On December 14, we had our virtual Christmas Party in Zoom and tried to create a festive atmosphere. Although we had very much hoped to be able to celebrate in person this year, we made the best out of the current situation. With a Christmas Quiz, we made ourselves familiar with different Christmas ...

On November 4, 2021, we celebrated the 278th birthday of FAU. Due to the pandemic, the celebration was realized as a television broadcast with a lot of exciting contributions and guests. Our president, Joachim Hornegger, gave an inspiring overview on what has happended during the past year with spec...

In September 2021, we started a new tradition and decided to meet in a restaurant for lunch every second week - whenever the current restrictions and regulations allow us to. In a time, when we often work from home, this gives us the opportunity to always stay in close contact, exchange our newest...